Hobson Prior are currently seeking for a Cellular Biology & Screening Team Leader/Senior Scientist to join a biotechnological organisation on a permanent basis located in Cambridge. For more information, please get in touch now!

Please note that to be considered for this role you must have the right to work in this location.

Key Responsibilities:

• Supporting one or more active drug discovery projects: developing and running biological assays, characterising hit and lead molecules, generating robust decision-making data & contributing to discussions on project planning and strategy.
• Development opportunity to become line manager in line with company growth.
• Developing relevant, novel and innovative cell-based and biochemical assays to address project challenges and support drug discovery projects in the area of oncology as well as applying these assays to screen and profile cellular activity of novel compounds and to interrogate target biology/disease relevant mechanisms.
• Contributing to wider development of the company's platform through characterising mode of action of lead molecules and assisting in discovery & characterisation of new mechanisms.
• Contributing to discussions and work on target selection and project planning.
• Culturing human cell lines and using a range of technologies to generate new cell lines.
• Critically analysing project data and contributing ideas that will drive projects forward.
• Working in an interdisciplinary team to support research strategies and project goals.
• Working with external collaborators including CROs and academic experts to seek input and generate project data to answer specific questions.
• Participating in building out the research capabilities of the company's Biology group including establishing and growing the company's Cambridge labs.
• Presenting and communicating plans and results internally and, when needed, externally at international conferences.

Key Skills:

• Demonstrated excellence in independently planning and executing experiments as well as critical data analysis skills.
• Strong interpersonal communication and effective team working with a 'can-do' approach to problem solving.
• Excellent organisational and self-motivational skills, with track record of prioritising work and keeping to deadlines.
• Outstanding track record evidenced by publication and presentation record.

Requirements:

• A Ph.D in Biology, Pharmacology, Cell biology or a related discipline or a BSc/MSc degree with significant relevant experience of supporting drug discovery projects to achieve successful milestones and conclusions.
• Experience working as part of multi-disciplinary teams in a drug discovery setting in e.g. pharma, biotech or an academic drug discovery unit.
• Experience matrix managing and/or mentoring more junior colleagues.
• Strong experience in molecular and cellular biology techniques applied to the development of physiologically-relevant cellular assays and systems applied to target validation, compound characterisation and screening.
• A practical understanding and experience of designing and running a wide range of cellular and biochemical plate-based assay methods and technologies, including mass spectrometry, high content imaging (preferably using the Perkin Elmer Operetta), Western blot, fluorescence, HTRF/Alphascreen and luminescence.
• Expertise in mammalian cell culture and cloning, stable cell line generation, gene expression knockdown.
• Deep knowledge of mechanisms of disease biology in oncology, immunology and/or CNS disease.
• Evidence of significant scientific productivity and impact through your own personal contributions leading to projects reaching significant milestones.
• Familiarity with biology of ubiquitin-proteasome system or previous experience characterising Targeted Protein Degradation-based agents.
• Project management experience as demonstrated by previous role as project lead or lead biologist.

Apply now:

If you are interested in learning more or applying to this exciting opportunity then please click "Apply" and upload a copy of your CV. Alternatively, for further details or to talk directly to a life sciences recruitment specialist directly, please select "Contact me" at the top of this page.

Hobson Prior is a leading life sciences recruiter focused on finding exceptional people and matching them with the finest positions across the globe. Hobson Prior is acting as an Employment Agency in relation to this vacancy.