Upstream Scientist

Hobson Prior are in search for a Upstream Scientist to join a global pharmaceutical organisation who focuses on delivering pioneering medicines and vaccines. This role will be on a permanent basis and will be located in Belgium.

Please note that to be considered for this role you must have the right to work in this location.

Job Responsibilities:

• You will be accountable to lead autonomously the USP part of several drug substance development projects in parallel, driving implementation of latest industry trends and state-of-the-art technologies into current manufacturing processes, identifying and promoting opportunities for improvements aiming for scalable, high efficiency, robust, and cost-effective manufacturing processes with reduced-footprint.
• You will work closely with the Scale-up team from the development stages to ensure smooth transition throughout the scales required at the different project phases.
• Accountable to support the Development Unit Head in bringing the team to the next level in technical knowledge and best practices, proactively promoting initiatives.
• To perform timeline and resource planning estimations, design development strategies, plan experimental protocols, lead horizontally a team of technicians and operators to execute them, having a strong presence in the lab to ensure best practices, compliance with documentation practices and EHS standards.
• You will follow the Quality by Design approach to process development, leading multi-disciplinary Technical Risk Assessments and ensuring to meet all documentation deliverables required at each of the project stage gates
• Ensure a strong interface and knowledge sharing with, Manufacturing Science and Technology, manufacturing strategy, site management, Process Science, and engineering departments for building related activities such as revamping, scaling-up or tech transfer to new facilities.
• You will closely collaborate with the In-Process Analytical organization to develop IPA strategy and implement IPA testing's as fit for upstream processes.
• To write and review project reports including process history files, process development reports, etc.

Key Skills:

• You are motivated by process development form lab scale to manufacturing scale.
• Capability to work in a dynamic multidisciplinary environment.
• Ability to embrace changes positively and adapt.
• Sound scientific methodology, critical thinking and problem-solving skills.
• Ability to act as a leader both in the lab and management of a small team technician.

Requirements:

• Master in bio-engineering, biochemistry, biotechnology, chemistry or equivalent.
• You hold a first experience in Upstream Drug Substance Development and/or Manufacturing in biopharma/ biotech industry.
• An in-depth understanding of Quality by Design approach and deliverables.
• Demonstrated knowledge in process development of recombinant proteins and viral vaccines based on different type of Hosts.
• Demonstrated knowledge of legacy, current-gen and next-gen vaccine manufacturing technologies.

Apply now:

If you are interested in learning more or applying to this exciting opportunity then please click "Apply" and upload a copy of your CV. Alternatively, for further details or to talk directly to a life sciences recruitment specialist directly, please select "Contact me" at the top of this page.

Hobson Prior is a leading life sciences recruiter focused on finding exceptional people and matching them with the finest positions across the globe. Hobson Prior is acting as an Employment Agency in relation to this vacancy.