Hobson Prior are looking for a Senior Translational Scientist (Oncology) to join a Swiss global biopharmaceutical organisation on a permanent basis. You will work in close collaboration with other Translational Medicine functions (DMPK, Preclinical Safety and Diagnostics/Personalized Medicine) and the Clinical Research Development teams to characterize the pharmacological properties of drug candidates.

Job Responsibilities:

• Represents the Pharmacology and Screening function in the Translational Medicine Project Teams. (may represent the Translational Medicine function in the global Project Teams and lead a Translational Medicine Project Team.
• Accountable for designing and outsourcing (CROs or academic labs) the pharmacology studies, as well as analysing and reporting the results for a variety of oncology projects:
• Defines and manages the clinical PD studies (e.g. blood and tissue biomarkers), incl. data analysis and reporting according to GCP and GCLP.
• Contributes to preparation of the pharmacology sections of regulatory documentation (IDB, summaries for IND and IMPD, briefing documentation). May participate in interactions with Health Authorities.
• In vitro/in vivo compounds selection and profiling, including off target characterization.
• Mechanism of action.
• In vivo proof of concept- PK/PD.
• Identification, method development/validation of clinical PD biomarkers.
• Contributes to in/out licensing activities for the assets of the company. Evaluates the pharmacology package of new opportunities and may interact with potential licensees.
• Partakes in external scientific communications (publications, poster and oral presentations).
• Supports the IP department by contributing to the scientific sections of patent applications.

Key Skills:

• Excellent team working skills.
• People management / leadership experience is desirable
• Strong interpersonal skill to communicate with external vendors and stakeholders.
• Fluent in English.
• Excellent communication and presentation skills (oral and written).
• Ability to influence through the matrix organization, demonstrated assertiveness and impact in communication.

Requirements:

• PhD in relevant expertise area or equivalent in biomedical engineering.
• In-depth expertise in preclinical pharmacology and oncology.
• A minimum of 5 years' experience in drug development (experience in clinical dev. is a plus)
• Experience in the industry is a plus.
• Good understanding of related disciplines including histopathology, bioanalytics, PK and PK/PD.
• Excellent IT analytical skills incl. advanced graphical explorations (R statistical software and image analysis are a plus).
• Project management experience.

Apply now:

If you are interested in learning more or applying to this exciting opportunity, please complete the form below and attach a copy of your CV. Alternatively, for further details or to talk directly to a life sciences recruitment specialist, please request a call back at the top of this page.

Hobson Prior is a leading life sciences recruiter focused on finding exceptional people and matching them with the finest positions across the globe. Hobson Prior is acting as an Employment Agency in relation to this vacancy.