MSAT Scientist Process Development (Downstream)

Hobson Prior is currently working with a gene therapy organisation who are determined to develop possible curative treatments for patients who are living with serious illnesses. This innovative company is seeking a MSAT Scientist Process Development (Downstream) to join them on a permanent basis in London.

Job Responsibilities:

• Develop downstream unit operations for the recovery and purification of AAV, including but not limited to chromatography, filtration and TFF.
• Accountable to support Manufacturing operations with implementing new processes and troubleshooting activities.
• You will build continuous understanding and knowledge of unit operations, to ensure process reproducibility and robustness.
• Scale up and tech transfer lab scale unit operations to in-house GMP production facility.
• Drive innovation and challenge conventional assumptions to ensure the organisation stays on the leading edge of manufacturing science and technology.
• Use appropriate process analytical tools to generate comprehensive and structured data, improve process understanding and identify optimization opportunities.

Key Skills:

• Analytical mindset.
• Excellent problem-solving skills.
• Change Management.
• Motivation.

Requirements:

• PhD or EngD degree in a relevant Bioprocess/Biochemical/Process Engineering/Biochemistry field and 0-1-year biotech industry experience in process development and process scale up.
• MS degree in Bioprocess/Biochemical/Process Engineering or Biochemistry or equivalent and >1 year of biotech industry experience in process development and process scale up.
• BS degree in Bioprocess/Biochemical/Process Engineering or Biochemistry or equivalent and >2 years of biotech industry experience in process development and process scale up.
• Understanding of GMP and QbD considerations in a large-scale manufacturing environment.
• Knowledge of Engineering principles for scale-up of downstream bioprocess operations.
• Prior experience with developing and optimizing chromatography unit operations for the purification of biopharmaceutical products (e.g. MAbs, Virus, Vaccines).
• Prior experience with developing and optimizing TFF unit operations for the manufacture of biopharmaceutical products.
• Understanding and experience with statistical and modelling software and tools, such as DoE, multivariate analysis, statistical tests (ANOVA, t-test).
• Previous experience with running in-process assays such as qPCR, ELISA, HPLC, plate-based spectrometric assays.

Apply now:

If you are interested in learning more or applying to this exciting opportunity, please complete the form below and attach a copy of your CV. Alternatively, for further details or to talk directly to a life sciences recruitment specialist, please request a call back at the top of this page.

Hobson Prior is a leading life sciences recruiter focused on finding exceptional people and matching them with the finest positions across the globe. Hobson Prior is acting as an Employment Agency in relation to this vacancy.