A fantastic opportunity has arisen for a driven Scientist II - Upstream Process Development to execute and further improve the organisation's cell culture platform. This is an exciting opportunity to join a clinical-stage biopharmaceutical organisation on a permanent basis in Cambridge Massachusetts.

Please note that to be considered for this role you must have the right to work in this location.

Job Responsibilities:

• Self-sufficiently design and perform cell culture experiments related to development, scale-up and characterization of cell culture processes.
• Apply engineering principles in scaling up from bench to pilot and cGMP clinical manufacturing scale.
• Establish linkage between upstream bioreactor process parameters and /or media conditions to exosome yield and quality attributes.
• To maintain good communication and collaborate with Downstream, Analytics and Research groups to deepen process knowledge and structure-activity relationships.
• Resolve technical problems by applying keen knowledge of experimental design, underlying scientific principles, and the ability to analyse and assess results.
• Manage and maintain process data in an organized manner, this includes writing/revising SOPs, authoring technical reports, tech transfer documents and preparing scientific presentations as needed.
• Partake and drive decision-making within the project team by actively engaging in and leading scientific and technical discussions.
• To author scientific manuscripts and patents. Present work internally and externally.
• Ensure effective, high-quality, timely and appropriate documentation in electronic lab notebooks.

Key Skills:

• Ability to troubleshoot, design/execute thoughtful experiments, and implement innovative solutions.
• Strong work ethic with capability to work independently and in a collaborative environment.
• Excellent communication and presentation skills (oral and written).

Requirements:

• Advance degree in biochemistry, biochemical engineering or related scientific discipline with an appropriate amount of relevant industry experience (PhD 2+ years, MS 8+ years).
• Advanced knowledge of scientific principles, mammalian cell culture research, and implementation strategies
• Hands on experience with bioreactors (bench and pilot/production scale) is required.
• Experience in development and transfer of production processes for biologics, with specific expertise desirable with viral vectors or nanoparticles to cGMP manufacturing organizations.
• Prior experience in supporting regulatory filings for drug substance manufacturing is desirable.

Apply now:

If you are interested in learning more or applying to this exciting opportunity then please click "Apply" and upload a copy of your CV. Alternatively, for further details or to talk directly to a life sciences recruitment specialist directly, please select "Contact me" at the top of this page.

Hobson Prior is a leading life sciences recruiter focused on finding exceptional people and matching them with the finest positions across the globe. Hobson Prior is acting as an Employment Agency in relation to this vacancy.